Scientific papers
Scientific paper
NUTRIOSE®, a useful tool for satiety, weight management and metabolic improvements

There is a strong epidemiologic support that dietary fibre intake can help with weight loss and management of some chronic diseases (Slavin 2005, Slavin 2008). However, given the extreme variability in viscosity, solubility in the gut, fermentation profiles, and hormonal responses, dietary fibers differ widely in the degree of satiety and health benefits they provide. Different mechanisms of actions may be involved to explain how of dietary fibres act on it. Viscosity has often been considered of first importance, as viscous soluble fibres increase gastric distension and may prolong intestinal phase of digestion and absorption through thickened gastric content, resulting in extended sensation of fullness (Slavin and Green 2007). Hormonal response including glycemic control may also be involved, as delayed gastric emptying and slowed energy and nutrient absorption decrease postprandial glucose levels. Moreover, the fermentability of dietary fibre in the colon has been increasingly described as important to generate specific effects on satiety and glycemia through the release of short chain fatty acids and gut peptides such as glucagon-like peptide-1 (Delzenne et al.2005). Dietary fibre could also play a role in the management of the metabolic syndrome through its ability to control body weight evolution and to modulate glucose homeostasis or insulin sensitivity.
NUTRIOSE® resistant dextrin, a non viscous soluble dietary fibre, has yielded supportive evidence in this context. Two human clinical trials have shown its effects on satiety, weight management and determinants of Metabolic Syndrome.



